Record details

Title
    Support for the initial attachment, growth and differentiation of MG-63 cells: a comparison between nano-size hydroxyapatite and micro-size hydroxyapatite in composites
Author
    Bačáková, Lucie
    Balík, Karel
    Filová, Elena
    Lisá, Věra
    Sucharda, Zbyněk
    Suchý, Tomáš
    Šlouf, Miroslav
    Šupová, Monika
    Žaloudková, Margit
Language
    anglicky
Publication type
    článek v odborném periodiku
Source title - serial
    International Journal of Nanomedicine
Vol./nr.
    Roč. 9, č. 1
Pages
    s. 3687-3706
Year
    2014
Notes
    Koresp. Filová
    Projekt: ED1.1.00/02.0109, GA MŠk, CZ3cav_un_auth*0295577
    Projekt: GA106/09/1000, GA ČR, CZ3cav_un_auth*0253154
    Projekt: NT13297, GA MZd, CZ3cav_un_auth*0281608
    Rozsah: 20 s.
Subject category
    composite materials
    hydroxyapatie
    nanoparticles
    osteoblasts
Keyword
    Attachment
    Cells
    Comparison
    Composites
    Differentiation
    Growth
    Hydroxyapatite
    Initial
    MG-63
    Micro-size
    Nano-size
    Support
Abstract (in english)
   Higher concentrations of micro-sized HA (ie. 20%-25% micro-sized HA) significantly reduced the growth and the viability of MG-63 cells. A concentration range of 5-15 vol% (HA/matrix) of both nano-sized and micro-sized HA particles seems to be the optimum for colonizing the composite with osteoblasts. These composites can potentially be used in medical applications
Contributor
    AV ČR Brno, Ústav struktury minerálů a hornin
Contributor code
    AV ČR, ÚSMH
Source format
    U
Import date
    24. 10. 2014